Skip to main content
. Author manuscript; available in PMC: 2020 Nov 5.
Published in final edited form as: Science. 2018 Mar 15;360(6385):176–182. doi: 10.1126/science.aam8999

Fig. 5. Gene expression patterns and spatial origin of cell types in the spinal cord.

Fig. 5.

(A) Re-clustering spinal cord nuclei resulted in 30 neuronal and 14 non-neuronal clusters. (B) GABAergic neurons were defined by expression of Gad1 and Gad2. A subset of GABAergic neurons are also glycinergic, based on expression of Slc6a5. Glutamatergic neurons were defined by expression of VGLUT1 (Slc17a6), whereas cholinergic motor neurons express Chat. (C) Novel gene markers distinguish gamma motor neurons from alpha motor neurons. (D) Inferred spatial origin of neuronal clusters within the spinal cord. We analyzed the Allen Spinal Cord Atlas expression patterns of the top ten enriched genes in each cluster. Dark purple indicates expression of all ten genes in the given region, while white indicates none of the ten genes were expressed in the given region.