TABLE 3. Characteristics of laboratory-confirmed infection among infants born to pregnant women with laboratory-confirmed SARS-CoV-2 infection — SET-NET, 13* jurisdictions, March 29–October 14, 2020.
| Characteristic | No. of infants (%) [Total no. of infants with available information] |
|||
|---|---|---|---|---|
| Total |
Not tested or missing data† |
RT-PCR positive results |
RT-PCR negative results |
|
| N = 2,869 (100.0) | N = 2,259 (78.7) | N = 16 (0.6)§ | N = 594 (20.7) | |
|
Maternal symptom status
|
[1,871]
|
[1,475]
|
[13]
|
[383]
|
| Asymptomatic |
231 (12.3) |
127 (8.6) |
4 (30.8) |
100 (26.1) |
| Symptomatic |
1,640 (87.7) |
1,348 (91.4) |
9 (69.2) |
283 (73.9) |
|
Timing of maternal infection¶
|
[1,851]
|
[1,440]
|
[14]
|
[398]
|
| ≤7 days before delivery |
740 (40.0) |
456 (31.7) |
11 (84.6) |
273 (68.6) |
| 8–10 days before delivery |
77 (4.2) |
56 (3.9) |
1 (7.7) |
20 (5.0) |
| >10 days before delivery |
1,034 (55.9) |
928 (64.4) |
1 (7.7) |
105 (26.4) |
| Median (IQR) days from mother’s first positive test to delivery |
17 (2–53) |
28 (3–63) |
1 (0–4) |
2 (0–12) |
| Maximum days from mother’s first positive test to delivery |
191 |
191 |
12 |
132 |
|
Gestational age at birth
|
[2,692]
|
[2,085]
|
[16]
|
[591]
|
| Term (≥37 wks) |
2,349 (87.3) |
1,849 (88.7) |
8 (50) |
492 (83.2) |
| Late preterm (34–36 wks) |
237 (8.8) |
168 (8.1) |
3 (18.8) |
66 (11.2) |
| Moderate to very preterm (<34 wks) |
106 (3.9) |
68 (3.3) |
5 (31.3) |
33 (5.6) |
| Infant ICU admission of term infants** n/N (%) | 276/2,315 (11.9) | 202/1,818 (11.1) | 1/8 (12.5) | 73/489 (14.9) |
Abbreviations: ICU = intensive care unit; IQR = interquartile range; RT-PCR = reverse transcription–polymerase chain reaction.
*Including California [excluding Los Angeles County], Houston, Los Angeles County, Michigan, Minnesota, Nebraska, New Jersey, North Dakota, Oklahoma, Pennsylvania [excluding Philadelphia], Puerto Rico, Tennessee, and Vermont.
† A total of 313 (10.9%) live births were reported as not tested during birth hospitalization, the remainder had no testing results reported.
§ First positive test result occurred on the second day of life for 11 infants, on the third day for four, and on the fourth day for one.
¶ Defined as either date of specimen collection for first positive test or symptom onset if exact date of collection was missing.
**Among term (≥37 weeks) infants only. Reason for admission could include need for isolation of an otherwise asymptomatic infant based on possible SARS-CoV-2 exposure.