Table 2. Changes in clinical outcomes: Secondary and exploratory outcomes by group allocation.
| Change from baseline within group | Between-group differences adjusted for baseline and practice* | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Control (n = 16) |
BS (n = 45) |
BS plus SF (n = 44) |
BS versus control | BS+SF versus control | BS+SF versus BS | ||||||||||
| Secondary Outcomes | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | p-value | Mean | 95% CI | p-value | Mean | 95% CI | p-value |
| LDL cholesterol (mmol/L) | −0.14 | (−0.48, 0.19) | −0.39 | (−0.59, −0.19) | −0.14 | (−0.34, 0.07) | −0.15 | (−0.47, 0.16) | 0.338 | 0.04 | (−0.28, 0.36) | 0.790 | 0.2 | (−0.03, 0.43) | 0.095 |
| HDL cholesterol (mmol/L) | 0.08 | (−0.03, 0.19) | −0.01 | (−0.08, 0.05) | −0.02 | (−0.09, 0.04) | −0.11 | (−0.24, 0.01) | 0.081 | −0.13 | (−0.26, 0.00) | 0.047 | −0.02 | (−0.11, 0.07) | 0.713 |
| Total cholesterol (mmol/L) | −0.13 | (−0.46, 0.21) | −0.46 | (−0.66, −0.25) | −0.14 | (−0.35, 0.06) | −0.3 | (−0.62, 0.02) | 0.069 | −0.02 | (−0.34, 0.30) | 0.910 | 0.28 | (0.04, 0.51) | 0.02 |
| Triglycerides (mmol/L) | −0.14 | (−0.54, 0.26) | −0.14 | (−0.38, 0.11) | −0.01 | (−0.25, 0.24) | 0.04 | (−0.37, 0.46) | 0.836 | 0.27 | (−0.15, 0.69) | 0.211 | 0.22 | (−0.09, 0.53) | 0.154 |
| Non−HDL cholesterol (mmol/L) | −0.21 | (−0.56, 0.14) | −0.44 | (−0.65, −0.24) | −0.12 | (−0.33, 0.09) | −0.16 | (−0.51, 0.19) | 0.362 | 0.15 | (−0.20, 0.50) | 0.393 | 0.31 | (0.06, 0.56) | 0.016 |
| Total cholesterol/HDL ratio | −0.15 | (−0.59, 0.29) | −0.34 | (−0.60, −0.07) | 0.02 | (−0.24, 0.29) | −0.13 | (−0.64, 0.37) | 0.601 | 0.25 | (−0.26, 0.76) | 0.335 | 0.38 | (0.01, 0.75) | 0.042 |
| Nonefficacy Outcomes | |||||||||||||||
| Systolic blood pressure (mmHg) | 0.5 | (−6.3, 7.4) | 1.3 | (−2.8, 5.4) | 1.2 | (−3.0, 5.3) | 0.58 | (−7.01, 8.18) | 0.879 | 1.44 | (−6.23, 9.11) | 0.710 | 0.86 | (−4.68, 6.40) | 0.759 |
| Diastolic blood pressure (mmHg) | 1.2 | (−2.7, 5.2) | −0.3 | (−2.7, 2.0) | −0.5 | (−2.9, 1.9) | −1.42 | (−5.80, 2.97) | 0.523 | −0.01 | (−4.50, 4.48) | 0.997 | 1.41 | (−1.87, 4.69) | 0.397 |
| Weight (kg) | −0.2 | (−1.5, 1.1) | −1.1 | (−1.9, −0.3) | −0.8 | (−1.6, 0.0) | −1.00 | (−2.52, 0.53) | 0.197 | −0.57 | (−2.11, 0.98) | 0.468 | 0.43 | (−0.69, 1.55) | 0.449 |
* Estimates from linear regression models adjusting for GP practice and baseline values, all p-values > 0.05.
BS, brief support; GP, general practioner; HDL, high-density lipoprotein; LDL, low-density lipoprotein; SF, brief support plus shopping feedback.