Table 1. Patient characteristics.
Training-Data Set | Validation-Data Set | |||||
---|---|---|---|---|---|---|
SVR Mean (SD) n = 57 | non-SVR Mean (SD) n = 29 | p value | SVR Mean (SD) n = 52 | non-SVR Mean (SD) n = 35 | p value | |
Age (years) | 65.75 (11.09) | 67.58 (7.88) | 0.78* | 69.04 7.93) | 67.46 (10.05) | 0.55* |
Sex (male/female) | 9/20 | 25/32 | 0.25** | 12/23 | 20/32 | 0.69** |
Platelet count (×104/μL) | 14.15 (7.38) | 30.74 (54.13) | 0.38* | 16.44 (6.73) | 27.7 (40.82) | 0.45* |
Aspartate aminotransferase (U/L) | 60.09 (30.99) | 56.42 (30.53) | 0.44* | 57.65 (36.89) | 59.7 (35.25) | 0.83* |
Alanine aminotransferase (U/L) | 55.93 (42.56) | 50.46 (57.35) | 0.27* | 56.37 (40.79) | 62.17 (53.41) | 0.88* |
Albumin (g/dL) | 3.98 (0.44) | 4.08 (0.28) | 0.53* | 4.06 (0.40) | 4.04 (0.34) | 0.87* |
Total bilirubin (mg/dL) | 0.83 (0.28) | 0.77 (0.23) | 0.42* | 0.82 (0.33) | 1.03 (0.82) | 0.42* |
HCV RNA (log IU/mL) | 6.23 (0.49) | 6.45 (0.62) | 0.09*** | 6.41 (0.52) | 6.56 (0.46) | 0.17*** |
DCV+ASV/SOF+LDV/SOF+LDV+RBV | 29/28/0 | 22/5/2 | 30/22/0 | 28/6/1 | 0.95 |
DCV: Daclatasvir, ASV: Asunaprevir, SOF: Sofosbuvir, LDV: Ledipasvir, RBV: Ribavirin,
* Wilcoxon test (Mann–Whitney U-test),
** Chi-square test,
*** One-way analysis of variance (ANOVA).