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. 2020 Nov 5;15(11):e0242028. doi: 10.1371/journal.pone.0242028

Table 1. Patient characteristics.

Training-Data Set Validation-Data Set
SVR Mean (SD) n = 57 non-SVR Mean (SD) n = 29 p value SVR Mean (SD) n = 52 non-SVR Mean (SD) n = 35 p value
Age (years) 65.75 (11.09) 67.58 (7.88) 0.78* 69.04 7.93) 67.46 (10.05) 0.55*
Sex (male/female) 9/20 25/32 0.25** 12/23 20/32 0.69**
Platelet count (×104/μL) 14.15 (7.38) 30.74 (54.13) 0.38* 16.44 (6.73) 27.7 (40.82) 0.45*
Aspartate aminotransferase (U/L) 60.09 (30.99) 56.42 (30.53) 0.44* 57.65 (36.89) 59.7 (35.25) 0.83*
Alanine aminotransferase (U/L) 55.93 (42.56) 50.46 (57.35) 0.27* 56.37 (40.79) 62.17 (53.41) 0.88*
Albumin (g/dL) 3.98 (0.44) 4.08 (0.28) 0.53* 4.06 (0.40) 4.04 (0.34) 0.87*
Total bilirubin (mg/dL) 0.83 (0.28) 0.77 (0.23) 0.42* 0.82 (0.33) 1.03 (0.82) 0.42*
HCV RNA (log IU/mL) 6.23 (0.49) 6.45 (0.62) 0.09*** 6.41 (0.52) 6.56 (0.46) 0.17***
DCV+ASV/SOF+LDV/SOF+LDV+RBV 29/28/0 22/5/2 30/22/0 28/6/1 0.95

DCV: Daclatasvir, ASV: Asunaprevir, SOF: Sofosbuvir, LDV: Ledipasvir, RBV: Ribavirin,

* Wilcoxon test (Mann–Whitney U-test),

** Chi-square test,

*** One-way analysis of variance (ANOVA).