Fig 6. Immunological response to repeated oral GS-986 administration in SIV-infected, ART-treated infant RMs.

Frequency of (A) CD38⁺ and (B) CD69⁺ peripheral CD4⁺ and CD8⁺ T cells immediately prior to, 1 day post, and 14 days post oral GS-986 dose 1, 5, and 10 in TV+TLR7 or equivalent sample day in control RMs. (C) Frequency of CD169⁺ classical, intermediate, and nonclassical monocytes in TV+TLR7 and control RMs. Dose number is indicated by color. Bars represent mean ± SEM. Statistical analysis was performed using a Wilcoxon matched-pairs signed rank test.