Table 1. Experimental division of SIV-infected, ART-treated infant macaques.
| Group | ID | Sex | A01 Status | Age at infection, weeks | Virus | CD4 Freq, baseline | CD4 Freq, ART initiation |
Peak PVL, pre-ART | AUC PVL, pre-ART |
|---|---|---|---|---|---|---|---|---|---|
| ART-only controls | RJc19 | M | + | 4.4 | SIVmac251 | 73.5% | 68.5% | 3.05E+07 | 5.61E+07 |
| RKc19 | F | + | 4.1 | SIV mac251 | 70.6% | 67.1% | 1.27E+07 | 2.00E+07 | |
| RPe19 | M | - | 4.3 | SIV mac251 | 73.0% | 65.1% | 3.51E+07 | 8.81E+07 | |
| RGc19 | M | - | 9.6 | SIVmac239 | 76.3% | 68.3% | 4.32E+07 | 1.39E+08 | |
| RYi19 | F | - | 3.9 | SIV mac251 | 50.6% | 53.8% | 1.56E+07 | 2.40E+07 | |
| RFj19 | F | - | 5.4 | SIV mac251 | 69.6% | n/a | 1.03E+06 | 1.99E+06 | |
| RLn19 | M | - | 4.4 | SIV mac251 | 72.7% | 62.7% | 1.01E+08 | 1.71E+08 | |
| RWo19 | F | - | 3.7 | SIV mac251 | 74.5% | 62.4% | 9.84E+06 | 2.07E+07 | |
| TV+TLR7a | RNd19 | M | - | 5.4 | SIV mac251 | 65.2% | 56.8% | 1.98E+07 | 4.32E+07 |
| RPd19 | F | - | 5.3 | SIV mac251 | 81.9% | 74.1% | 1.78E+07 | 3.24E+07 | |
| RBe19 | F | - | 5 | SIV mac251 | 80.1% | 80.2% | 1.98E+08 | 3.30E+08 | |
| RCc19 | M | + | 10 | SIVmac239 | 85.7% | 70.4% | 2.16E+06 | 2.73E+06 | |
| RUl19 | M | - | 4.9 | SIV mac251 | 67.5% | 62.7% | 3.20E+07 | 5.68E+07 | |
| RMm19 | M | - | 5.9 | SIV mac251 | 70.5% | 62.9% | 1.85E+06 | 1.92E+06 | |
| RPq19 | F | + | 3.3 | SIV mac251 | 76.9% | 73.7% | 5.01E+06 | 8.07E+06 | |
| RAq19 | M | + | 4.9 | SIV mac251 | 69.7% | 64.1% | 1.03E+07 | 2.31E+07 |
aTV+TLR7, therapeutic vaccination with Ad48/MVA+GS-986.