Figure 2.

GASL1 GASL1 restrained MKN45 and SGC-7901 cell proliferation

Overexpression of GASL1 meaningfully declined (a) cell viability, (b) BrdU and (c-e) cyclinD1 levels but strengthened p53 and p21 levels in cells. At the same time, silencing GASL1 meaningfully strengthened cell viability, BrdU and cyclinD1 levels but declined p53 and p21 levels in cells. Data were expressed as mean  ±  SD and compared by two-way ANOVA followed by Tukey’s multiple comparison test (n = 3 per group).* P < 0.05; ** P < 0.01; *** P < 0.001.