Table 2.
Demographic and clinical characteristics associated with each SIV uptake transition – Hazard ratios and 95% confidence intervals – Two-state Markov model estimates (EGB, France, 2006/07–2015/16, n = 16,026)
| No SIV → SIV (ref. No SIV → No SIV) |
SIV → No SIV (ref. SIV → SIV) |
|
|---|---|---|
| aHR [95% CI] | ||
| Sociodemographic characteristics | ||
| Men (ref. Women) | 1.09 [1.04;1.14] | 0.84 [0.80;0.88] |
| Age at inclusion (ref. ≤ 55 years) | ||
| 56–64 | 1.32 [1.24;1.41] | 0.67 [0.62;0.72] |
| 65–84 | 1.39 [1.30;1.48] | 0.44 [0.41;0.47] |
| ≥ 85 | 1.57 [1.40;1.76] | 0.47 [0.43;0.53] |
| Clinical characteristics | ||
| Patients with newly identified diabetes in 2006a (ref. No) | 1.28 [1.09;1.50] | 0.97 [0.71;1.32] |
| Type and treatment of diabetes at season n-1/n (ref. Other type diabetes without any treatment) | ||
| Other type diabetes treated by insulin and/or antidiabetic drugs | 1.08 [1.00;1.17] | 0.71 [0.65;0.79] |
| Type 1 diabetesb | 1.32 [1.19;1.47] | 0.73 [0.64;0.83] |
| Weighted individual chronic condition scorec at season n-1/n (ref. Min-Q1) | ||
| Q1-median | 1.39 [1.30;1.49] | 0.92 [0.85;0.99] |
| Median-Q3 | 1.55 [1.45;1.67] | 0.94 [0.87;1.01] |
| Q3-Max | 1.87 [1.74;2.02] | 0.98 [0.91;1.06] |
| Hospitalized for diabetes or its complications during year n-1 | 1.12 [1.02;1.24] | 1.04 [0.94;1.16] |
| Hospitalized for influenza or its complications between during year n-1 | 1.35 [1.06;1.72] | 1.23 [0.96;1.58] |
| Healthcare use | ||
| Number of consultations with general practitioner > median during year n-1 (ref. No) | 1.29 [1.23;1.36] | 0.99 [0.94;1.05] |
| Consultation during year n-1 (ref. No) with: | ||
| Pulmonologist | 1.41 [1.24;1.60] | 0.94 [0.81;1.08] |
| Endocrinologist | 1.00 [0.93;1.07] | 0.90 [0.84;0.97] |
| Cardiologist | 1.02 [0.96;1.08] | 0.80 [0.75;0.85] |
| Change of general practitioner at season n/n-1 (ref. No) | 1.11 [1.02;1.21] | 1.14 [1.04;1.25] |
| A(H1N1) pandemic season (ref. before pandemic) | ||
| Year of pandemic (2009/2010) | 1.37 [1.28;1.47] | 0.84 [0.76;0.93] |
| Year following pandemic (2010/2011) | 0.57 [0.51;0.62] | 1.76 [1.64;1.90] |
| After 2010/2011 | 0.76 [0.72;0.81] | 1.11 [1.04;1.18] |
Abbreviations: aHR [95% CI], adjusted hazard ratio [95% confidence interval]; SIV, seasonal influenza vaccination.
aPatients with newly identified diabetes were those not detected as having diabetes the year before inclusion.
bPeople with type 1 diabetes were those with long-term illness status for type 1 diabetes (E10 according to the ICD-10) and treated by insulin at inclusion.
cThe individual chronic condition score (ICC) was calculated as a weighted sum of 21 chronic conditions. Weights account for the severity of each condition in the score calculation (ICC range in study cohort: min = 0; max = 3.7).