Table 1.
Overall sample characteristics by sex
| Parameters | Females N=455 Mean (SD) |
Males N=539 Mean (SD) |
p-value |
|---|---|---|---|
| Age | 71.8 (7.2) | 73.7 (7.1) | <0.001 |
| Education (years) | 15.6 (2.6) | 16.7 (2.6) | <0.001 |
| Race (% Caucasian) | 90.9 | 94.1 | 0.06 |
| APOE4 carrier (%) | 43.5 | 44.1 | 0.84 |
| Global cognition (MMSE) | 27.5 (2.9) | 27.3 (2.8) | 0.12 |
| CDR-SOB | 1.5 (1.9) | 1.7 (1.9) | 0.05 |
| RAVLT immediate recall | 40.4 (13.2) | 34.0 (12.3) | <0.001 |
| RAVLT delayed recall | 5.7 (4.7) | 4.2 (4.0) | <0.001 |
| Cortical [18F]AV45 SUVR | 1.21 (0.22) | 1.19 (0.23) | 0.37 |
Note. MMSE = Mini Mental State Exam. RAVLT = Rey Auditory Verbal Learning Test. CDR-SOB = Clinical Dementia Rating – Sum of Boxes. SUVR = Standardized uptake value ratio.