Table 1.
EBV and high-risk HPVs detection in human colorectal cancer cases and their association with tumor grade
EBV/HPVs Statusa | EBV+/HPVs+ | EBV+/HPVs− | EBV−/HPVs+ | EBV−/HPVs− |
---|---|---|---|---|
Number of Samplesb | 17 (17) | 20 (20) | 38 (37) | 27 (26) |
Tumor Grade | ||||
High | 10 (59) | 3 (15) | 8 (21) | 2 (7) |
Intermediate | 7 (41) | 9 (45) | 20 (53) | 11 (41) |
Low | 0 (0) | 8 (40) | 10 (26) | 14 (52) |
High & Intermediatec | 17 (100) | 12 (60) | 28 (74) | 13 (48) |
p-value | .0031** | .0155* | .0002** | |
Intermediate & Lowd | 7 (41) | 17 (85) | 30 (79) | 25 (93) |
p-value | .0056** | .0020** | .0001** |
aThese two methodologies, PCR and IHC, were used to detect the presence of EBV and high-risk HPVs.
bThe total number of samples examined in this study is 102.
() percentage
cHigh & Intermediate indicate the number of the samples of high and intermediate grade and their respective EBV/HPVs statuses and P value as follows: .0031 for EBV+/HPVs−, .0155 for EBV−/HPVs+ and .0002 for EBV−/HPVs−.
dIntermediate & Low show the number of the samples of intermediate and low grade with their respective EBV/HPVs ranks as well as P value: .0056 for EBV+/HPVs−, .0020 for EBV−/HPVs+ and .0001 for EBV−/HPVs−.