Table III.

Nicotine Transport and Partition Parameters Used in COMSOL Model Calculations. Parameters Were Estimated as in Dancik et al. (37) Unless Otherwise Noted

Parameter	Definition	Units	TDS	SCa	VE	DE
Di @ 32°C	Diffusivity	cm2 s−1	6 × 10−7	22.5 × 10−10	3.18 × 10−6	3.18 × 10−6
				0.90 × 10−10
Di @ 42°C	Diffusivity	cm2 s−1	6 × 10−7	50.6 × 10−10	3.84× 10−6	3.84 × 10−6
				2.01 × 10−10
Ki/w	Partition coefficient w/ respect to water	–	2.25	3.76	3.19	3.19
			2.22	9.11

^aFirst parameter listed applies to fully hydrated skin; second to partially hydrated skin (70)