Table 4.
Levels of Inflammatory markers and lymphocyte subsets of the study subjects according to disease severity of COVID-19
| Characteristic | Disease severity of COVID-19 |
Statistic parameter |
|||||
|---|---|---|---|---|---|---|---|
| Asymptomatic carriers (n = 50) | Mild cases (n = 81) | Ordinary cases (n = 486) | Severe or critical cases (n = 31) | F value/Chi-Square | P value | ||
| Inflammatory marker | |||||||
| Erythrocyte sedimentation rate (mm/h) | 7.00 (4.25–13.00) (n = 32) |
11.00 (5.00–25.75) (n = 38) |
18.00 (8.00–32.00) (n = 239) |
58.00 (33.50–75.00) (n = 17) |
37.498 | < 0.001 | |
| C-reactive protein > 10.0 mg/L |
7/39 (17.9) | 12/62 (19.4) | 173/359 (48.2) | 23/26 (88.5) | 49.374 | < 0.001 | |
| Procalcitonin (ng/mL) |
0.03 (0.02–0.10) (n = 23) |
0.03 (0.02–0.05) (n = 38) |
0.04 (0.02–0.08) (n = 241) |
0.15 (0.06–0.28) (n = 14) |
13.243 | 0.004 | |
| Interleukin-6 (pg/mL) |
0.01 (0.01–0.02) (n = 11) |
0.01 (0.01–2.32) (n = 21) |
0.02 (0.01–0.04) (n = 92) |
0.03 (0.03–0.15) (n = 5) |
5.774 | 0.123 | |
| Lymphocyte subset | |||||||
| CD3 + T lymphocytes (/µL) | 1411.54 ± 671.25 (n = 13) |
1431.06 ± 577.90 (n = 16) |
1045.06 ± 501.65 (n = 89) |
486.60 ± 266.28 (n = 5) |
6.219 | 0.001 | |
| CD4 + T lymphocytes (/µL) | 782.69 ± 366.39 (n = 13) |
712.56 ± 350.52 (n = 16) |
577.25 ± 300.94 (n = 89) |
307.80 ± 164.67 (n = 5) |
3.803 | 0.012 | |
| CD8 + T lymphocytes (/µL) | 451.00 (286.50–634.00) (n = 13) |
532.00(329.25–663.50) (n = 16) |
316.00(216.00–526.50) (n = 89) |
144.00 (62.50–259.00) (n = 5) |
15.533 | 0.001 | |
CD: cluster of differentiation.