Table 6.
Antioxidant activities of 400 mg/kg/day of CVE and IGE in TZM-intoxicated rat cardiac tissue.
| Groups | Antioxidant parameters | |||||
|---|---|---|---|---|---|---|
| GSH | GST | GPx | SOD | CAT | MDA | |
| I | 26.8 ± 3.0 | 31.7 ± 1.1 | 28.5 ± 2.8 | 08.4 ± 0.6 | 44.5 ± 1.2 | 0.4 ± 0.1 |
| II | 35.0 ± 3.6 | 29.3 ± 0.9 | 32.5 ± 3.3 | 07.7 ± 0.5 | 42.0 ± 6.8 | 0.5 ± 0.3 |
| III | 33.5 ± 4.5 | 22.9 ± 1.7 | 24.8 ± 1.8 | 06.2 ± 0.9 | 33.4 ± 7.2 | 0.5 ± 0.1 |
| IV | 16.7 ± 2.1c- | 19.8 ± 2.2c- | 46.9 ± 2.0f+ | 03.6 ± 0.2c- | 17.7 ± 2.4c- | 0.8 ± 0.1f+ |
| V | 29.5 ± 3.3b+ | 24.7 ± 0.6b+ | 19.9 ± 1.1f- | 06.5 ± 0.7c+ | 26.0 ± 2.6b+ | 0.5 ± 0.1f- |
| VI | 28.3 ± 1.6b+ | 25.0 ± 0.5b+ | 19.6 ± 1.8f- | 08.1 ± 0.6c+ | 26.9 ± 1.2b+ | 0.4 ± 0.1f- |
| VII | 34.8 ± 2.7c+ | 26.4 ± 0.5c+ | 16.7 ± 2.1f- | 07.6 ± 0.7c+ | 30.2 ± 2.6c+ | 0.5 ± 0.1f- |
c- represents a significant decrease at p < 0.0001 when compared to Groups I-III (controls) values while f+ represents a significant increases at p < 0.0001 when compared to Groups I-III values; b+ and c+ represent significant increases at p < 0.05 and p < 0.0001, respectively, when compared to Groups IV values while f- represents a significant decrease at p < 0.0001 when compared to untreated positive control (TZM treated only, Group IV).