Table 2.
Metabolic data from the four groups after 8 weeks of dietary treatment.
| LDL-R−/− ND | LDL-R−/− HFD | LDL-R−/− HFD+TQ | |
|---|---|---|---|
| Heart/BW (mg/g) | 4.175 ± 0.1966 | 3.814 ± 0.3045 | 4.483 ± 0.08 |
| TC (mmol/L) | 8.5 ± 1.207∗ | 34.01 ± 2.318 | 14.08 ± 0.7108∗ |
| LDL-c (mmol/L) | 3.938 ± 0.1281∗ | 23.88 ± 1.651 | 6.783 ± 0.6817∗ |
| hs-CRP (ng/dL) | 58.5 ± 4.252∗ | 221.2 ± 13.43 | 111.7 ± 10.19∗# |
| IL-6 (pg/mL) | 18.1 ± 1.9266∗ | 79.956 ± 4.0109 | 43.33 ± 6.9251∗# |
| TNF-α (pg/mL) | 19.156 ± 4.7569∗ | 88.708 ± 3.6499 | 45.262 ± 4.0316∗# |
Abbreviations: BW: body weight; TC: total cholesterol; LDL-c: low-density lipoprotein-cholesterol; IL-6: interleukin-6; TNF-α: tumor necrosis factor-α. Data are means ± SEM; n = 5-6 per group. ∗P < 0.05 vs. LDL-R−/− HFD; #P < 0.05 vs. LDL-R−/− ND.