. 2020 Oct 30;20(5):313–323. doi: 10.17245/jdapm.2020.20.5.313

Table 1. The inclusion criteria, exclusion criteria and withdrawal criteria for this study.

Inclusion criteria	Exclusion criteria
1. Age of participants between 18 and 30 years 2. Participants with asymptomatic bilateral symmetrical partially or totally impacted lower third molars classified as the inclination according to the Winter classification [20] and position according to the Pell and Gregory classification [21]. 3. This study required flap opening, bone removal, and tooth separation during the operation. 4. The operation site was free from infection and inflammation at the time of operation.	1. Participants with systemic disorders contraindicated the surgical procedure. 2. Facial deformities of the participants that may interfere with the injections during the operation or the evaluation. 3. Smoking, alcoholism, pregnancy or lactation. 4. Allergy to drugs or other substances used in this study. 5. Analgesic intake within the 2 weeks before surgery. 6. Usage of other drugs besides the drugs in this study. 7. Inability to honor the follow-up appointments and refusal to participate in the study. 8. Surgical duration exceeding 60 minutes. 9. Any surgical complications occurred that would render the non-comparable procedures.
Withdrawal criteria	The participants can withdraw from the study at any time.

Inclusion criteria

Exclusion criteria

1. Age of participants between 18 and 30 years
2. Participants with asymptomatic bilateral symmetrical partially or totally impacted lower third molars classified as the inclination according to the Winter classification [20] and position according to the Pell and Gregory classification [21].
3. This study required flap opening, bone removal, and tooth separation during the operation.
4. The operation site was free from infection and inflammation at the time of operation.

1. Participants with systemic disorders contraindicated the surgical procedure.
2. Facial deformities of the participants that may interfere with the injections during the operation or the evaluation.
3. Smoking, alcoholism, pregnancy or lactation.
4. Allergy to drugs or other substances used in this study.
5. Analgesic intake within the 2 weeks before surgery.
6. Usage of other drugs besides the drugs in this study.
7. Inability to honor the follow-up appointments and refusal to participate in the study.
8. Surgical duration exceeding 60 minutes.
9. Any surgical complications occurred that would render the non-comparable procedures.

Withdrawal criteria

The participants can withdraw from the study at any time.