Table 1. Baseline participants demographics and clinical characteristics.
| Clinical characteristics | SPB-201 (n = 38) | Placebo (n = 41) | Total (n = 79) | p value | |
|---|---|---|---|---|---|
| Sex | 0.3331† | ||||
| Male | 26 (68.42) | 32 (78.05) | 58 (73.42) | ||
| Female | 12 (31.58) | 9 (21.95) | 21 (26.58) | ||
| Age (yr) | 0.6794* | ||||
| Mean ± SD | 48.00 ± 12.63 | 49.20 ± 12.94 | 48.62 ± 12.73 | ||
| Min–Max | 20.00–67.00 | 19.00–73.00 | 19.00–73.00 | ||
| Weight (kg) | 0.6881* | ||||
| Mean ± SD | 76.02 ± 16.15 | 77.45 ± 15.93 | 76.77 ± 16.05 | ||
| Min–Max | 48.1–117.4 | 53.2–144.5 | 48.1–144.5 | ||
| BMI (kg/m2) | 0.3499* | ||||
| Mean ± SD | 26.65 ± 3.87 | 27.53 ± 4.26 | 27.10 ± 4.10 | ||
| Min–Max | 18.24–34.79 | 22.48–47.73 | 18.24–47.73 | ||
| Exercise | 0.8229‡ | ||||
| No | 14 (36.84) | 18 (43.90) | 32 (40.51) | ||
| 1–2 times/week | 9 (23.68) | 12 (29.27) | 21 (26.58) | ||
| 3–4 times/week | 10 (26.32) | 8 (19.51) | 18 (22.78) | ||
| 5–6 times/week | 3 (7.89) | 2 (4.88) | 5 (6.33) | ||
| Everyday | 2 (5.26) | 1 (2.44) | 3 (3.80) | ||
| Smoking | 0.2203† | ||||
| No | 22 (57.89) | 20 (48.78) | 42 (53.16) | ||
| Ex-smoker (over a year) | 3 (7.89) | 9 (21.95) | 12 (15.19) | ||
| Smoker | 13 (34.21) | 12 (29.27) | 25 (31.65) | ||
| HFD | 0.8381† | ||||
| No | 4 (10.53) | 6 (14.63) | 10 (12.66) | ||
| 1–2 times/week | 27 (71.05) | 27 (65.85) | 54 (68.35) | ||
| 3 or more/week | 7 (18.42) | 8 (19.51) | 15 (18.99) | ||
SD, standard deviation; BMI, body mass index; HFD, high fat diet.
*The p value by 2 sample t-test; †p value by χ2 test; ‡p value by Fisher's exact test.