Table 2.

Variation in acidification and proteolytic activities in hMDM from healthy donors (n = 53) in response to IgG, TDM, and β- glucan beads.

Acidification	30 min			60 min			90 min
	Range	% CV (mean ± SD)	P	Range	% CV (mean ± SD)	P	Range	% CV (mean ± SD)	P
IgG	0.99–1.13	2.75 (1.05 ± 0.03)		1.00–1.25	4.96 (1.13 ± 0.06)		1.02–1.29	5.69 (1.14 ± 0.07)
TDM	0.97–1.10	2.92 (1.02 ± 0.03)	0.6	1.00–1.19	4.34 (1.08 ± 0.05)	0.39	1.01–1.23	4.71 (1.11 ± 0.05)	0.34
β-glucan	0.98–1.10	2.53 (1.03 ± 0.03)		1.01–1.19	4.16 (1.09 ± 0.05)		1.01–1.25	4.9 (1.12 ± 0.05)
Proteolysis	60 min			120 min			180 min
	Range	% CV (mean ± SD)	P	Range	% CV (mean ± SD)	P	Range	% CV (mean ± SD)	P
IgG	1.34–6.08	38.89 (2.48 ± 0.97)		2.22–21.06	48.82 (7.71 ± 3.76)		2.67–29.28	46.27 (11.25 ± 5.21)
TDM	1.41–5.91	38.75 (2.51 ± 0.97)	0.77	2.61–19.38	47.82 (7.16 ± 3.42)	0.96	3.27–24.57	44.68 (10.28 ± 4.59)	0.98
β-glucan	1.31–6.81	42.97 (2.62 ± 1.12)		2.82–22.04	50.15 (8.02 ± 4.02)		3.78–29.26	45.76 (11.55 ± 5.28)

Mean ± SD, Mean ± standard deviation; CV, coefficient variation, calculated by percentage of SD divided by mean.

P, P-value for comparison of coefficient variation in either acidification or proteolytic activity among three ligands.