Table 3.
Variation in acidification and proteolytic activities in hMDM from LTB (n = 35) and ATB (n = 101) in response to TDM beads.
Acidification | 30 min | 60 min | 90 min | ||||||
---|---|---|---|---|---|---|---|---|---|
Range | % CV (mean ± SD) | P | Range | % CV (mean ± SD) | P | Range | % CV (mean ± SD) | P | |
LTB | 0.97–1.10 | 3.12 (1.02 ± 0.03) | 0.32 | 1.00–1.19 | 3.97 (1.09 ± 0.04) | 0.41 | 1.02–1.23 | 4.53 (1.12 ± 0.05) | 0.39 |
ATB | 0.98–1.10 | 2.75 (1.03 ± 0.03) | 1.00–1.23 | 4.52 (1.1 ± 0.05) | 1.00–1.32 | 5.14 (1.14 ± 0.06) | |||
Proteolysis | 60 min | 120 min | 180 min | ||||||
Range | % CV (mean ± SD) | P | Range | % CV (mean ± SD) | P | Range | % CV (mean ± SD) | P | |
LTB | 1.45–5.91 | 36.53 (2.71 ± 0.99) | 0.24 | 2.80–19.38 | 42.87 (8 ± 3.43) | 0.08 | 3.53–24.57 | 39.98 (11.42 ± 4.57) | 0.03 |
ATB | 1.00–4.85 | 30.61 (2.91 ± 0.89) | 1.74–15.3 | 32.95 (8.56 ± 2.82) | 2.31–21.27 | 29.1 (12.12 ± 3.53) |
LTB, Latent tuberculosis; ATB, Active tuberculosis.
Range, min-max; Mean ± SD, Mean ± standard deviation; CV, coefficient variation, calculated by percentage of SD divided by mean.
P, P-value for comparison of coefficient variation in either acidification or proteolytic activity among two groups.