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. 2020 Oct 23;10:586101. doi: 10.3389/fcimb.2020.586101

Table 3.

Variation in acidification and proteolytic activities in hMDM from LTB (n = 35) and ATB (n = 101) in response to TDM beads.

Acidification 30 min 60 min 90 min
Range % CV (mean ± SD) P Range % CV (mean ± SD) P Range % CV (mean ± SD) P
LTB 0.97–1.10 3.12 (1.02 ± 0.03) 0.32 1.00–1.19 3.97 (1.09 ± 0.04) 0.41 1.02–1.23 4.53 (1.12 ± 0.05) 0.39
ATB 0.98–1.10 2.75 (1.03 ± 0.03) 1.00–1.23 4.52 (1.1 ± 0.05) 1.00–1.32 5.14 (1.14 ± 0.06)
Proteolysis 60 min 120 min 180 min
Range % CV (mean ± SD) P Range % CV (mean ± SD) P Range % CV (mean ± SD) P
LTB 1.45–5.91 36.53 (2.71 ± 0.99) 0.24 2.80–19.38 42.87 (8 ± 3.43) 0.08 3.53–24.57 39.98 (11.42 ± 4.57) 0.03
ATB 1.00–4.85 30.61 (2.91 ± 0.89) 1.74–15.3 32.95 (8.56 ± 2.82) 2.31–21.27 29.1 (12.12 ± 3.53)

LTB, Latent tuberculosis; ATB, Active tuberculosis.

Range, min-max; Mean ± SD, Mean ± standard deviation; CV, coefficient variation, calculated by percentage of SD divided by mean.

P, P-value for comparison of coefficient variation in either acidification or proteolytic activity among two groups.