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. 2020 Oct 23;10:586101. doi: 10.3389/fcimb.2020.586101

Table 4.

Variation in acidification and proteolysis activities in hMDM from PTB (n = 60) and TBM (n = 64) in response to TDM beads.

Acidification 30 min 60 min 90 min
Range % CV (mean ± SD) P Range % CV (mean ± SD) P Range % CV (mean ± SD) P
PTB 0.98–1.09 2.69 (1.03 ± 0.03) 0.78 1.02–1.23 4.59 (1.11 ± 0.05) 0.66 1.02–1.32 4.83 (1.14 ± 0.06) 0.77
TBM 0.98–1.1 2.77 (1.03 ± 0.03) 1–1.22 4.3 (1.1 ± 0.05) 1–1.27 5.01 (1.13 ± 0.06)
Proteolysis 60 min 120 min 180 min
Range % CV (mean ± SD) P Range % CV (mean ± SD) P Range % CV (mean ± SD) P
PTB 1.31–5.4 29.3 (2.97 ± 0.87) 0.28 3.59–14.96 32.08 (8.47 ± 2.72) 0.35 6.14–19.74 28.51 (11.81 ± 3.37) 0.35
TBM 1.09–4.85 34.2 (2.79 ± 0.95) 1.74–15.30 37.13 (8.21 ± 3.05) 2.31–21.27 32.85 (11.78 ± 3.87)

PTB, Pulmonary tuberculosis; TBM, Tuberculosis meningitis Range, min-max; Mean ± SD, Mean ± standard deviation; CV, coefficient variation, calculated by percentage of SD divided by mean. P, P value for comparison of coefficient variation in either acidification or proteolytic activity among two groups.