Table 2.

Univariate and multivariate Cox regression analyses of cancer-specific survival of patients with bladder urothelial carcinoma

Variables	Univariate analysis			Multivariate analysis
	HR	95% CI	p value	HR	95% CI	p value
Age (years)	1.031	0.894–1.220	0.463
Sex	1.108	0.912–1.365	0.574
Tumor size	1.566	1.206–2.118	0.015	1.429	1.283–1.804	0.007
Pathological grade	1.325	1.186–1.660	0.024	1.213	0.944–1.589	0.147
Tumor multiplicity	1.291	0.847–1.693	0.282
Lymphovascular invasion	1.838	1.337–2.506	< 0.001	1.692	1.360–2.054	0.003
Squamous differentiation	1.492	1.255–1.906	0.032	1.220	0.921–1.759	0.188
Glandular differentiation	1.190	0.751–1.543	0.238
Recurrence	3.451	2.683–5.770	< 0.001	3.856	3.007–5.402	< 0.001
Progression	2.947	2.380–4.136	< 0.001	2.655	2.103–3.458	< 0.001
SSH-1 expression	1.693	1.235–2.106	< 0.001	1.558	1.192–2.043	0.015