Table 1.
Baseline, treatment, and surgical characteristics of patients who underwent single-stage buccal mucosal graft urethroplasty for radiation-induced bulbomembranous urethral stricture
| Patient number; N (%) | 47 (100) |
| Age at surgery (years); median (IQR) | 70 (65–74) |
| ASA™ score; N (%) | |
| 1 | 2 (4.3) |
| 2 | 22 (47) |
| 3 | 23 (49) |
| 4 | 0 (0) |
| Body mass index; median (IQR) | 27 (26–30) |
| Coronary heart disease; N (%) | 17 (36) |
| Diabetes mellitus; N (%) | 10 (21) |
| Hypertension; N (%) | 32 (68) |
| Smoking status; N (%) | |
| Never | 19 (40) |
| Ever | 28 (60) |
| Anticoagulants/antiplatelets; N (%) | |
| None | 25 (53) |
| Aspirin | 15 (32) |
| Clopidogrel | 1 (2.1) |
| Oral anticoagulants* | 6 (13) |
| RT indication; N (%) | |
| Prostate cancer | 45 (96) |
| Rectal cancer | 1 (2.1) |
| Bladder cancer | 1 (2.1) |
| RT modality; N (%) | |
| LDR brachytherapy | 5 (11) |
| External beam RT | 33 (70) |
| HDR brachytherapy + external beam RT | 8 (17) |
| High-intensity focused ultrasound | 1 (2.1) |
| Prostate cancer surgery (N = 45); N (%) | |
| None | 12 (26) |
| Radical prostatectomy | 24 (51) |
| TURP† | 10 (21) |
| Retropubic adenomectomy | 1 (2.1) |
| History of direct vision internal urethrotomy; N (%) | |
| None | 18 (38) |
| 1 | 12 (26) |
| 2–5 | 15 (32) |
| ≥ 6 | 2 (4.3) |
| History of urethroplasty; N (%) | |
| None | 45 (96) |
| 1 | 1 (2.1) |
| ≥ 2 | 1 (2.1) |
Proportions may not add up to 100%, as they are rounded
ASA™ American Society of Anesthesiologists™, HDR high dose rate, IQR interquartile range, LDR low dose rate, RT radiation therapy, TURP transurethral resection of the prostate
*Patients with oral anticoagulants were switched to a low-molecular-weight heparin preoperatively
†One patient underwent TURP and subsequent high-intensity focused ultrasound