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. 2020 Oct 6;22:791–802. doi: 10.1016/j.omtn.2020.10.001

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© 2020 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Toxicity of Intraperitoneal Administration of AmNA-Modified Anti-SYT13 ASOs

(A) Liver function after treatment for 4 weeks. (B) Appearance (twice weekly groups), histological findings (twice weekly groups), and volumes of the liver and brain after treatment for 4 weeks. (C) Total volume of peritoneal nodules of each treatment group. (D) SYT13 mRNA levels in the peritoneal nodules. (E) Blood tests after 2 weeks administration of 0.2 mg hSYT13-4378 or hSYT13-4733, twice weekly and 2 weeks after treatment ceased. Error bars indicate the standard deviation.