Table 2.
Paths | Effect | 95% CI | p |
---|---|---|---|
Effects from CA to Outcome | |||
CA → ΔBMI → Chronic Illness | .026* | [.010,.056] | .026 |
CA → ΔBMI → Cardiometabolic Risk | .089** | [.038,.140] | .000 |
CA → ΔBMI → DNAm PhenoAge | .025* | [.009,.059] | .036 |
Effects from GRSO to Outcome | |||
GRSO → ΔBMI → Chronic Illness | .022* | [.006,.046] | .030 |
GRSO → ΔBMI → Cardiometabolic Risk | .075** | [.030,.123] | .001 |
GRSO → ΔBMI → DNAm PhenoAge | .021* | [.007,.050] | .035 |
Note:
p ≤ .01;
p ≤ .05 (two-tailed tests), n = 412. CI = Confidence interval; BMI = Body mass index. GRSO = Genetic risk score for obesity. Diagnostic VIF scores for all variables were below 10, ranging from 1.08 to 1.52, indicating no evidence of multicollinearity among the study variables.