Table 3.
Comparison of requirements for [6xCu]CuCl2 separation vs. other recent literature [reagents for target preparation and recycling not considered]
| This study | (Ohya et al. 2016, 2019) | (Matarrese et al. 2010) | (Jalilian et al. 2007) | (Strangis and Lepera 2007) | (Thieme et al. 2012) | |
|---|---|---|---|---|---|---|
| Product isotope | 61Cu | 64Cu | 60/64Cu | 64Cu | 61Cu | 64Cu |
| Starting material | natNi | 64Ni | 60/64Ni | 68Zn | natNi | 64Ni |
| Automated | Yes | Yes | Yes | No b | Partial | Partial |
| Disposable cassette-based purification | Yes | No | No | No | No | No |
| Prep. Time | < 1 h | 1 day | - a | - a | - a | - a |
| Process time (min) | 65 ± 3 | ~ 150 | ≥ 42 b | 105 | 90–120 | ~ 200 |
| Total process acid consumption | 160 mmol | > 200 mmol | 460 mmol | > 1000 mmol | - a | > 85 b |
| Organics | No | Acetone | No | No | No | No |
| Radiochemical yield (%) | 90.4 ± 3.2 | 88 ± 3 | 95 | 95 | 25–48 | > 90 |
| Formulation as stated | 2 mL, < 0.1 M HCl | Evaporated then reconstituted in ≥10 mL UPW | 10 mL, 0.5 M HCl | 50 mL, 2 M HCl | - a | Evaporated then reconstituted in 0.4 mL, 0.01 M HCl |
acould not be determined from article
bnot explicitly stated, assumed from context