TABLE 2.

Univariate and multivariable regression analysis for major complications

Variable	Univariate logistic regression		Multivariable logistic regression
	OR (95% CI)	p value	OR (95% CI)	p value
All histologies
Age
< 65 years	Reference		Reference
≥ 65 years	1.66 (1.12–2.46)	0.01	1.72 (1.08–2.75)	0.02
Gender
Female	Reference
Male	1.01 (0.73–1.42)	0.94
Race
White	Reference
Black	1.44 (0.75–2.79)	0.27
Other	1.18 (0.69–2.01)	0.54
BMI
≤ 18.5	Reference
18.5–24.9	1.04 (0.34–3.15)	0.95
25–29.9	0.91 (0.29–2/76)	0.87
30–34.9	1.06 (0.34–3.31)	0.93
35–39.9	1.11 (0.33–3.71)	0.86
≥ 40	0.67 (0.17–2.63)	0.56
Functional status
Independent	Reference
Partially dependent/totally dependent	2.03 (0.58–7.09)	0.27
Neoadjuvant chemotherapy
No neoadjuvant chemotherapy	Reference
Received neoadjuvant chemotherapy	1.18 (0.84–1.66)	0.35
Histology
Non-invasive appendiceal	Reference		Reference
Invasive appendiceal	1.75 (1.15–2.66)	0.01	2.15 (1.36–3.37)	< 0.01
PCI (median, IQR)
PCI < 13	Reference		Reference
PCI ≥ 13	2.65 (1.86–3.77)	< 0.01	2.13 (1.38–3.29)	< 0.01
CCR
CCR0	Reference		Reference
CCR1	2.01 (1.43–2.81)	< 0.01	1.58 (0.64–3.92)	0.32
Non-invasive histology
Age
< 65 years	Reference
≥ 65 years	1.75 (0.77–3.99)	0.18
Gender
Female	Reference
Male	0.58 (0.27–1.22)	0.15
Race
White	Reference
Black	1.50 (0.35–6.36)	0.65
Other	1.80 (0.61–5.36)	0.31
BMI
≤ 18.5	Reference
18.5–24.9	0.84 (0.35–2.03)	0.49
25–29.9	0.95 (0.29–3.10)	0.90
30–34.9	1.69 (0.56–5.19)	0.25
35–39.9	1.07 (0.19–6.10)	0.95
≥ 40	0 (0)	0.83
Functional status
Independent	Reference
Partially dependent/totally dependent	-	-
Neoadjuvant chemotherapy
No neoadjuvant chemotherapy	Reference
Received neoadjuvant chemotherapy	0.51 (0.11–2.44)	0.40
PCI (median, IQR)
PCI < 13	Reference
PCI C 13	1.44 (0.67–3.09)	0.35
CCR
CCR0	Reference
CCR1	1.46 (0.71–3.00)	0.30
Invasive histology
Age
< 65 years	Reference		Reference
≥ 65 years	1.79 (1.05–3.06)	0.03	2.04 (1.16–3.59)	0.01
Gender
Female	Reference
Male	1.10 (0.71–1.71)	0.67
Race
White	Reference
Black	1.25 (0.54–2.89)	0.60
Other	0.49 (0.23–1.05)	0.07
BMI
≤ 18.5	Reference
18.5–24.9	0.91 (0.19–4.3)	0.91
25–29.9	0.79 (0.17–3.68)	0.76
30–34.9	0.94 (0.19–4.54)	0.94
35–39.9	0.74 (0.14–3.99)	0.73
≥ 40	1.67 (0.23–12.22)	0.52
Functional status
Independent	Reference
Partially dependent/totally dependent	0.38 (0.04–3.39)	0.38
Neoadjuvant chemotherapy
No neoadjuvant chemotherapy	Reference
Received neoadjuvant chemotherapy	1.15 (0.74–1.79)	0.54
PCI (median, IQR)
PCI < 13	Reference		Reference
PCI ≥ 13	2.90 (1.93–4.61)	< 0.01	2.66 (1.62–4.37)	< 0.01
CCR
CCR0	Reference		Reference
CCR1	1.94 (1.24–3.04)	< 0.01	1.50 (0.91–2.48)	0.11

Bold values indicate statistical significance with a p value of < 0.05