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. Author manuscript; available in PMC: 2021 Feb 28.
Published in final edited form as: Nat Struct Mol Biol. 2020 Aug 31;27(11):1017–1023. doi: 10.1038/s41594-020-0490-9

Fig. 3: HDX-MS difference of SLC38A9NT reveals pre-GAP complex dynamics.

Fig. 3:

a, HDX difference plot of SLC38A9NT in complex with inactive Rags and in isolation at 6 s exchange time. Plotted are the mean ± SD of technical replicates (n=4). b, Uptake difference mapped onto SLC38A9NT in the pre-GAP complex structure. Boundaries of the N-core and the solvent exposed loop are indicated. c, Residues shown to be crucial for SLC38A9 function in vivo (red) mapped onto the pre-GAP complex structure. Data for graph in a is available as source data online.