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. 2020 Nov 5;10:19119. doi: 10.1038/s41598-020-75064-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Gene ontology (GO) enrichment analysis results showing GO enrichment analyses for biological processes affected in regimen 2 (top panel and C–D comparison from Fig. 3), and regimen 3 (bottom panel, B–C comparison from Fig. 3). Biological functions are represented as upregulated (red) and downregulated (blue) and are size scaled based on calculated fold enrichment of our differentially expressed genes dataset compared to drosophila database.