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. 2020 Nov 1;14(1):100925. doi: 10.1016/j.tranon.2020.100925

Table 3.

Independent risk factors of tumor size and tumor stages in multivariate analysis.

Clinicopathological features Subtype Factor P value HR 95% CI
Lower Upper
Tumor size >5cm GC-NENM TG 0.014 0.499 0.287 0.867
HDL-C <0.001 0.493 0.348 0.699
GC-NEC HDL-C 0.042 0.666 0.450 0.986
Advanced stages (pT>1) GC-NENM Size <0.001 2.067 1.632 2.619
TG 0.023 0.399 0.181 0.879
GC-NEC Size <0.001 2.189 1.660 2.886
Late stages (stage III+IV) GC-NENM Age 0.001 0.969 0.951 0.987
Size <0.001 1.406 1.173 1.685
TG 0.002 0.279 0.124 0.628
HDL-C 0.001 0.363 0.203 0.648
LDL-C 0.002 1.899 1.274 2.830
GC-NEC BMI 0.020 0.946 0.903 0.991
Size <0.001 1.565 1.240 1.977

GC-NENM: gastric cancer expressing neuroendocrine markers but no neuroendocrine morphology; GC-NEC: mixed carcinoma with adenocarcinoma and neuroendocrine components; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; BMI: body mass index; HR: hazard ratio; CI: confidential interval.