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(a) Synthesis of glycol-AuNPs. (b) Con A immobilized on the sensor surface. (c) Binding kinetics monitoring the changes in frequency (ΔF) vs. time with different concentrations of Man-AuNPs. (d) Changes in frequency (ΔF) with the build-up of the multilayer. Reproduced from ref. 69 and 70 with permission from The Royal Society of Chemistry, copyright 2010 and 2013.
