Table 10.
Binding parameters of glyco-NP-lectin interactions obtained from DLS.81
| Entry | Glyco-NP | Particle size | Ligand density | Lectin | Kd (μM) | EFa |
|---|---|---|---|---|---|---|
| 1 | Man-SNP | 35 nm | 830 | Con A | 0.063 | 9 |
| 2 | 110 nm | 2,600 | Con A | 0.97 | 0.2 | |
| 3 | 470 nm | 4,900 | Con A | 9.2 | 0.01 | |
| 4 | Man-AuNP | 40 nm | 950 | Con A | 0.086 | 6 |
| 5 | Gal-SNP | 35 nm | 840 | RCA120 | 0.22 | 2 |
KD: 470 μM (Man-Con A); 455 μM (Gal- RCA120)