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Dissociate constants of Man2, Man2-AuNPs, Man3 or Man3-AuNPs with domain A or B of CVNQ50C. The numbers in parentheses are the enhancement factors (EF=KD/(Kd × Number of Man2 on Man2-AuNP (or Man3 on Man3-AuNP), where KD is the dissociate constant of Man2/3 and Kd is the dissociate constant of Man2/3-AuNPs).35
| Domain A | Domain B | |
|---|---|---|
| Man2 | 700 ± 50 μM | 64 ± 4 μM |
| Man2-AuNP | 56.4 ± 7 nM (8.2) | 0.24 ± 0.1 nM (176) |
| Man3 | 3.4 ± 0.2 μM | 43 ± 2 μM |
| Man3-AuNP | 0.011 ± 0.007 nM (309) | 11.8 ± 2.3 nM (3.6) |
