Table 1.
Demographics and ocular characteristics of study population.
| Normal (n = 68) | NTG (n = 100) | P value* | |
|---|---|---|---|
| Eyes (n) | 68 | 100 | |
| Sex (M/F) | 20/48 | 53/47 | 0.002 |
| Age at recruitment (years) | 57.71 (11.09) | 58.86 (12.0) | 0.097 |
| Hypertension, n (%) | 21 (30.88%) | 31 (31%) | 0.987 |
| Obstructive sleep apnea, n (%) | 0 (0%) | 8 (8%) | 0.017 |
| Cerebrovascular accident, n (%) | 3 (4.41%) | 1 (1%) | 0.26 |
| Ischaemic heart disease, n (%) | 6 (8.82%) | 6 (6%) | 0.485 |
| SBP (mmHg) | 139.57 (21.58) | 134.74 (20.26) | 0.141 |
| DBP (mmHg) | 81.71 (12.07) | 80.18 (9.91) | 0.372 |
| IOP (mmHg) | 14.07 (2.93) | 14.88 (2.95) | 0.084 |
| CCT (microns) | 543.87 (34.25) | 535.4 (33.03) | 0.11 |
| Spherical errors (D) | − 0.69 (2.52) | − 3.19 (3.87) | < 0.001 |
| Axial length (mm) | 24.08 (1.23) | 25.53 (1.76) | < 0.001 |
| SAP MD (dB) | 0.18 (0.90) | − 6.73 (5.49) | < 0.001 |
| SAP PSD (dB) | 1.62 (0.34) | 7.41 (4.11) | < 0.001 |
| SAP VFI (%) | 99.29 (0.83) | 82.42 (16.64) | < 0.001 |
| Average RNFL thickness, Cirrus (μm) | 95.04 (9.58) | 72.41 (10.24) | < 0.001 |
CCT central corneal thickness; DBP diastolic blood pressure; IOP intraocular pressure; MD mean deviation; NTG normal tension glaucoma; PSD pattern standard deviation; VFI visual field index; RNFL retinal nerve fiber layer; SAP standard automated perimetry; SBP systolic blood pressure.
*Statistical significance tested by independent samples t test (for continuous variables) or Chi-square test (for categorical variables).