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. 2020 Nov 5;10:19117. doi: 10.1038/s41598-020-76050-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Admission values of urinary nephrin, immunoglobulin G (IgG), α1-microglobulin (α1-MG) and serum soluble urokinase plasminogen activator receptor (suPAR) levels in relation to the extent of total proteinuria (protein-to-creatinine ratio, PCR) in patients with acute hantavirus infection (n = 26) and age and gender-matched, healthy controls (n = 18). Horizontal lines represent upper range limits of normal values when available. (B) Exemplary urinary nephrin and PCR courses of two hantavirus patients in relation to serum creatinine. gCr = gram creatinine, HD = hemodialysis, PCR = protein-to-creatinine ratio, dpo = days post onset of first symptoms, SCr = serum creatinine.