Table 1.

Characteristics of 26 patients with acute hantavirus infection.

	All patients (n = 26) Median (Range)	Moderate PCR (≤ 2485 mg/gCr, n = 13) Median (Range)	Severe PCR (> 2485 mg/gCr, n = 13) Median (Range)	p-value
Age [years]	36.5 (18–62)	40 (18–61)	33 (23–62)	0.572
Sex [male/female]	19/7	9/4	10/3	0.658
Dpo [days]	6 (3–14)	7 (6–14)	6 (3–8)	0.006
Los [days]	5 (3–15)	4 (3–8)	6 (4–15)	0.006
Body weight gain [kg]	4.2 (0.1–12.8)	4.2 (0.10–12.8)	3.1 (0.9–10.1)	0.878
Laboratory parameters
SCr baseline	0.88 (0.65–1.83)	0.88 (0.68–1.05)	0.87 (0.65–1.83)	0.626
SCr on admission [mg/dL]	4.52 (1.38–10.40)	4.57 (1.93–7.84)	4.47 (1.38–10.40)	0.626
SCr max [mg/dL]	5.1 (1.93–18.02)	4.71 (1.93–8.46)	5.71 (2.57–18.02)	0.029
Urea max [mg/dL]	88.5 (38.0–221.0)	82.0 (38.0–221.0)	123.0 (59.0–210.0)	0.293
Serum albumin min [g/L]	35.4 (22.7–42.4)	36.3 (30.2–43.4)	34.8 (22.7–37.7)	0.209
CRP max [mg/L]	59.5 (4.2–151.3)	60.2 (4.2–139.8)	59.7 (17.2–151.3)	0.939
Hemoglobin min [g/dL]	12.3 (10.1–14.5)	12.2 (10.6–14.5)	12.7 (10.1–13.7)	0.472
Hematocrit min [L/L]	0.35 (0.30–0.44)	0.35 (0.31–0.44)	0.35 (0.30–0.40)	0.736
Platelets min [G/L]	126.5 (21.0–291.0)	138.0 (38.0–291.0)	96.0 (21.0–154.0)	0.021
Leukocytes max [G/L]	10.1 (5.0–14.5)	10.0 (5.4–11.8)	10.4 (5.0–14.5)	0.209
Hematuria max [cells/µL]	20.0 (3.0–1013.0)	19.0 (3.0–252.0)	21.0 (6.0–1013.0)	0.572
Leukocyturia max [cells/µL]	37.5 (5.0–265.0)	22.0 (5.0–130.0)	48.0 (10.0–256.0)	0.045
ACR max [mg/gCr]	1,592.9 (13.8–29,759.2)	425.2 (13.8–1,413.0)	4,177.0 (1,772.7–29,759.2)	< 0.0001
PCR max [mg/gCr]	2,930.6 (42.2–50,219.7)	642.9 (42.2–2,873.6)	8,394.0 (2,987.6–50,219.7)	< 0.0001

ACR = albumin-to-creatinine ratio, CRP = C-reactive protein, dpo = days post onset of first symptoms, gCr = gram creatinine, Los = length of hospital stay, max = maximum, min = minimum, PCR = protein-to-creatinine ratio, SCr = serum creatinine.

Bold values are statistically significant for p < 0.05.