Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 5;6:117. doi: 10.1038/s41420-020-00350-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — A, B Representative dotplots showing IL-34-producing cells in TICs or lamina propria mononuclear cells (LPMCs) isolated, respectively, from the tumoral and non-tumoral areas of one patient with CRC. Cells were gated on live CD45 + cells and subsequently analyzed for the expression of IL-34, CD3 (A) or CD19 (B) by flow cytometry. One of five representative experiments is shown. Staining with the IL-34 isotype control antibodies is also shown. C Representative dotplots showing IL-34-producing CD68 + TICs or LPMCs isolated as above. Cells were gated on CD45 + live cells and subsequently analyzed for the expression of IL-34 and CD68 by flow cytometry. The right panel shows live CD45 + CD68 + cells expressing IL-34 in TICs or LPMCs isolated from five patients with CRC. Each point in the graph indicates the percentage of live CD45 + CD68 + cells expressing IL-34 in a single sample of a single CRC patient. Horizontal bars indicate the median values.