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. 2020 Nov 5;10:19134. doi: 10.1038/s41598-020-76203-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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DeepZ, Z-Hunt and Chip-Seq Z-DNA predictions. (A) The region chr9:37,800,000–37,805,000—Z-DNA overlaps with the 1st exon of DCAF10 gene; (B) the region chr18:67,870,000–67,875,000—Z-DNA is located in the promoter area and overlaps with the first exon of RTTN gene; (C) the region chr16:67,905,000–67,910,000—Z-DNA is located in the regulatory area of two bidirectional genes EDC4 and NUTF4; Z-DNA overlaps with promoter area, 5′UTR and the first exon of EDC4 and upstream area of NUTF4 gene; (D) The region chr1:565,000–570,000 has a high potential to form Z-DNA; four non-coding RNAs are located in the region.