TABLE 3.
Hub genes with prognostic potential and the association between their expression and CRC patient survival.
| Gene name | Dataset | Endpoint | Cohort | Probe ID | N | COX P-value | HR [95% CI-low CI-upp] | Prognosis |
| NUSAP1 | GSE12945 | Overall survival | Berlin | 218039_at | 62 | 0.042761 | 3.84 [1.04–14.12] | Poorer |
| NUSAP1 | GSE12945 | Disease-free survival | Berlin | 219978_s_at | 51 | 0.01814 | 34.78 [1.83–660.48] | Poorer |
| NUSAP1 | GSE12945 | Overall survival | Berlin | 219978_s_at | 62 | 0.000504 | 34.32 [4.68–251.59] | Poorer |
| CCL28 | GSE17536 | Disease-free survival | MCC | 224240_s_at | 145 | 0.028541 | 0.49 [0.25–0.93] | Better |
| CCL28 | GSE14333 | Disease-free survival | Melbourne | 224027_at | 226 | 0.034875 | 0.82 [0.68–0.99] | Better |
| CCL28 | GSE14333 | Disease-free survival | Melbourne | 224240_s_at | 226 | 0.010374 | 0.66 [0.48–0.91] | Better |
| GPR15 | GSE17537 | Disease-free survival | VMC | 208524_at | 55 | 0.029864 | 0.08 [0.01–0.79] | Better |
| GPR15 | GSE17537 | Disease-specific survival | VMC | 208524_at | 49 | 0.043031 | 0.08 [0.01–0.92] | Better |
| PNOC | GSE17536 | Disease-specific survival | MCC | 205901_at | 177 | 0.02132 | 0.30 [0.11–0.84] | Better |
| PNOC | GSE17536 | Overall survival | MCC | 205901_at | 177 | 0.015574 | 0.34 [0.14–0.82] | Better |