Table 4.

Binding constants for competitive binding of compounds 1-5 in the presence of ibuprofen and warfarin.

Compound	Site marker	Ka (M−1)
1	Blank	5.06 × 103
	Warfarin	4.95 × 103
	Ibuprofen	2.11 × 103
2	Blank	4.29 × 105
	Warfarin	1.57 × 104
	Ibuprofen	6.46 × 104
3	Blank	1.06 × 109
	Warfarin	1.03 × 107
	Ibuprofen	5.24 × 107
4	Blank	3.83 × 106
	Warfarin	3.42 × 105
	Ibuprofen	3.10 × 104
5	Blank	1.79 × 105
	Warfarin	3.83 × 103
	Ibuprofen	3.55 × 103