Table 8.

Mean values (± SE) of the magnetic resonance imaging (MRI) markers (i.e., volumes of the total gray matter, total white matter, caudate, putamen, pallidum, accumbens, hippocampus, amygdale, and lateral ventricle; cortical thicknesses of the total cortex and entorhinal cortex; white matter hypointensity and lesions) as well as the results of their statistical comparisons (T-test on log-10 transformed data; p < 0.05 corrected) in the groups of noADMCI-noEEA (N = 19) and noADMCI-EEA (N = 13) patients.

	noADMCI-noEEA	noADMCI-EEA	T-test
MRI markers in noADMCI-noEEA and noADMCI-EEA
GLOBAL MARKERS
Normalized total WM volume	0.28 ± 0.01	0.30 ± 0.01	p = 0.1
Normalized total GM volume	0.40 ± 0.01	0.40 ± 0.01	p = 0.4
Cortical thickness	4.9 ± 0.1	4.8 ± 0.1	p = 0.1
BASAL GANGLIA MARKERS
Normalized caudate volume	0.0050 ± 0.0003	0.0047 ± 0.0001	p = 0.1
Normalized putamen volume	0.0061 ± 0.0002	0.0060 ± 0.0003	p = 0.4
Normalized pallidum volume	0.0024 ± 0.0001	0.0026 ± 0.0001	p = 0.1
Normalized accumbens volume	0.00058 ± 0.00004	0.00065 ± 0.00004	p = 0.1
MESIAL TEMPORAL MARKERS
Normalized hippocampus volume	0.0051 ± 0.0002	0.0051 ± 0.0002	p = 0.1
Normalized amygdale volume	0.0019 ± 0.0001	0.0020 ± 0.0001	p = 0.3
Entorhinal cortical thickness	6.7 ± 0.2	6.5 ± 0.3	p = 0.3
VENTRICULAR MARKERS
Normalized lateral ventricle volume	0.022 ± 0.003	0.018 ± 0.003	p = 0.1
Hypo-intensity/lesion WM markers
WM hypo-intensity	3,251 ± 515	2,310 ± 397	p = 0.1
WM lesions	2,541 ± 790	2,869 ± 959	p = 04

The volumes were normalized with reference to the total intracranial volume. All ADMCI patients had all values of those MRI markers available.

noADMCI-noEEA, patients with mild cognitive impairment not due to Alzheimer's disease and without epileptiform EEG activity; noADMCI-EEA, patients with mild cognitive impairment not due to Alzheimer's disease and epileptiform EEG activity. No significant difference was observed between the two noADMCI groups even when a marginal threshold of p < 0.05 uncorrected was used.