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. 2020 Oct 23;10:543646. doi: 10.3389/fonc.2020.543646

Table 2.

Multivariate analysis for OS.

Characteristic HR 95%CI P value
Gender 0.86 0.62–1.20 0.382
Age (year) 1.18 0.92–1.51 0.192
T stage 0.97 0.70–1.34 0.857
N stage 1.68 1.22–2.31 0.001
Metastatic sites 2.84 2.14–3.77 <0.001
Number of PCT cycles 0.79 0.61–1.02 0.075
Tumor response to PCT 1.75 1.35–2.26 <0.001
LRRT 0.52 0.40–0.68 <0.001

CI, confidence interval; HR, hazard ratio; PCT, palliative chemotherapy; LRRT, locoregional radiotherapy.

A Cox proportional hazards regression model was used to detect variables one by one without adjustment. All variables were transformed into categorical variables. HRs were calculated for Gender (Female vs. Male); Age (y) (>47 vs. ≤47); T stage (T3-4 vs. T1-2); N stage (N2-3 vs. N0-1); Metastatic sites (Multiple sites vs. Single site); Number of PCT cycle (>4 vs. ≤4); Tumor response to PCT (SD/PD vs. CR/PR); LRRT (Yes vs. No).