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. 2020 Oct 23;14:578900. doi: 10.3389/fnana.2020.578900

TABLE 1.

Volumes of the substantia nigra pars reticulata (SNpr), substantia nigra pars compacta (SNpc), and ventral tegmental area (VTA) in adolescence (postnatal day 35, P35) and adulthood (postnatal day 60, P60).

A/P coordinate 4.60–5.10 mm from bregma A/P coordinate 5.20–5.70 mm from bregma A/P coordinate 5.80–6.30 mm from bregma



Volume (mm3) Volume (mm3) Volume (mm3)



SNpr SNpr SNpr
P35 day P35 day P35 day
Control 0.45 ± 0.03 Control 0.46 ± 0.02 Control /
MD 0.68 ± 0.06 MD 0.81 ± 0.12 MD /
P60 day P60 day P60 day
Control 0.51 ± 0.01 Control 0.68 ± 0.04 Control /
MD 0.59 ± 0.02 MD 0.79 ± 0.01 MD /
SNpc SNpc SNpc
P35 day P35 day P35 day
Control 1.02 ± 0.05 Control 1.07 ± 0.07 Control 0.30 ± 0.01
MD 1.74 ± 0.25 MD 2.11 ± 0.18 MD 0.73 ± 0.03
P60 day P60 day P60 day
Control 1.37 ± 0.03 Control 1.61 ± 0.08 Control 1.39 ± 0.08
MD 1.83 ± 0.09 MD 2.02 ± 0.04 MD 1.78 ± 0.14
VTA VTA VTA
P35 day P35 day P35 day
Control 1.06 ± 0.06 Control 1.35 ± 0.15 Control 0.59 ± 0.02
MD 1.98 ± 0.13 MD 2.40 ± 0.26 MD 1.10 ± 0.16
P60 day P60 day P60 day
Control 1.23 ± 0.02 Control 1.69 ± 0.04 Control 1.43 ± 0.04
MD 2.12 ± 0.11 MD 2.43 ± 0.10 MD 1.75 ± 0.08

All results are presented as mean values ± SEM. Numbers in bold are statistically significant mean values at p ≤ 0.05.