TABLE 2.

Number of TH + neurons in the substantia nigra pars reticulata (SNpr), substantia nigra pars compacta (SNpc), and ventral tegmental area (VTA) in adolescence (postnatal day 35, P35) and adulthood (postnatal day 60, P60).

A/P coordinate 4.60 – 5.10 mm from bregma		A/P coordinate 5.20 – 5.70 mm from bregma		A/P coordinate 5.80–6.30 mm from bregma
Number of TH + neurons		Number of TH + neurons		Number of TH + neurons
	SNpr		SNpr		SNpr
P35 day		P35 day		P35 day
Control	17.2 ± 5.27	Control	19.7 ± 5.95	Control	/
MD	28.6 ± 2.56	MD	34.4 ± 7.30	MD	/
95% CI	11.4 ± 6.04	95% CI	14.7 ± 9.71	95% CI	/
P60 day		P60 day		P60 day
Control	15.1 ± 3.86	Control	20.75 ± 3.97	Control	/
MD	28.7 ± 2.69	MD	30.25 ± 5.58	MD	/
95% CI	13.5 ± 4.85	95% CI	9.50 ± 7.06
	SNpc		SNpc		SNpc
P35 day		P35 day		P35 day
Control	76.2 ± 20.83	Control	88.3 ± 6.76	Control	41.60 ± 13.32
MD	112.5 ± 15.81	MD	122.10 ± 16.25	MD	81.20 ± 8.40
95% CI	36.3 ± 26.97	95% CI	33.8 ± 18.15	95% CI	39.6 ± 16.24
P60 day		P60 day		P60 day
Control	83.50 ± 11.04	Control	80.75 ± 12.63	Control	40.00 ± 3.00
MD	109.75 ± 9.60	MD	112.5 ± 14.50	MD	78.87 ± 6.21
95% CI	26.25 ± 15.09	95% CI	31.75 ± 19.83	95% CI	38.87 ± 7.11
	VTA		VTA		VTA
P35 day		P35 day		P35 day
Control	68.70 ± 17.95	Control	79.5 ± 10.25	Control	41.9 ± 3.15
MD	117.8 ± 13.50	MD	111.10 ± 16.52	MD	70.30 ± 11.05
95% CI	49.1 ± 23.16	95% CI	31.6 ± 20.05	95% CI	28.4 ± 11.85
P60 day		P60 day		P60 day
Control	69.25 ± 8.87	Control	75.13 ± 4.71	Control	37.13 ± 5.94
MD	124.38 ± 12.67	MD	103.75 ± 9.99	MD	69.50 ± 19.87
95% CI	55.13 ± 15.95	95% CI	28.62 ± 11.39	95% CI	32.37 ± 21.39

All results are presented as mean values ± SEM. Numbers in bold are statistically significant mean values at p ≤ 0.05;[Frame2] CI, confidence interval.