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. 2020 Oct 23;11:591088. doi: 10.3389/fimmu.2020.591088

Table 1.

Oral organisms associated with distant tumors.

Cancer Organisms Sample type Reference
Esophageal cancer Increase of T. forsythia and P. gingivalis Oral rinse (64)
Esophageal cancer Streptococcus anginosus, S. mitis, Treponema denticola Saliva (65)
Esophageal cancer 3 taxon model: Lautropia, Streptococcus, and an unspecified genus of the order Bacteroidales. (AUC = 0.94) Oral swab (66)
Esophageal cancer Overall decreased microbial diversity in cancer patients Saliva (67)
Pancreatic cancer Porphyromonas gingivalis, Aggregatibacteractinomycetemcomitans Oral rinse (68)
Pancreatic cancer Porphyromonas gingivalis Blood (antibodies) (69)
Pancreatic cancer Fusobacterium spp. Tissue from pancreatic ductal adenocarcinoma (70)
Pancreatic cancer 2 taxon model: Streptococcus mitis and Neisseria elongata. (AUC =0.90) Saliva (71)
Pancreatic cancer Significative higher ratio of Leptotrichiato Porphyromonas was found in cancer patients. Saliva (72)
Pancreatic cancer Association with β-diversity and Haemophilus Saliva (73)
Pancreatic cancer Fusobacterium spp. Tissue samples, swabs, stool (74)
Pancreatic cancer Streptococcus thermophilus higher in cancer, and Haemophilus parainfluenzae and Neisseria flavescens lower in cancer Saliva (75)
Pancreatic cancer Haemophilus, Porphyromonas, Leptotrichia and Fusobacterium could distinguish cancer patients from healthy subjects Tongue coating microbiota (76)
Hepatic cancer Fusobacterium and Oribacterium. Increase in diversity. Tongue coat (77)
Lung cancer Capnocytophaga sp., Veillonella sp. Saliva (78)
Lung cancer Streptococcus and Veillonella Airway brushings (79)
Lung cancer Sphingomonas and Blastomonas Saliva (80)
Lung cancer Streptococcus and Veillonella Saliva (81)
Colorectal cancer T. denticola and Prevotella sp. oral taxon 313 Oral rinse (82)
Colorectal cancer Fusobacterium sp., Porphyromonas sp. Stool (83)
Colorectal cancer Fusobacterium sp. Colorectal cancer tissues (84)
Colorectal cancer Lactobacillus and Rothia Oral rinse (85)
Colorectal cancer Streptococcus and Prevotella spp. Oral swabcolonic mucosae and stools, colorectal polyps or controls (86)
Colorectal cancer Fusobacterium sp. Tissue and stool samples (87)
Colorectal cancer Fusobacterium nucleatum Colorectal tissue biopsies (88)
Colorectal cancer Fusobacterium sp. Colorectal tissue biopsies (89)
Colorectal cancer Fusobacterium sp. Colorectal tissue biopsies (21)
Colorectal cancer Fusobacterium sp., Lactococcus sp. Colorectal tissue biopsies (90)
Digestive tract cancer Actinomyces odontolyticus, Steptococcus parasinguinis, Corynebacterium spp., Neisseria spp.,TM7[G-1] sp., Porphyromonas gingivalis, Fusobacterium nucleatum, Neisseria elongata and Streptococcus sanguinis Saliva (91)
Colorectal cancer Fusobacterium nucleatum, Parvimonas micra, and Peptostreptococcus stomatis Colon tissue (92)
Colorectal cancer Peptostreptococcus stomatis, Fusobacteriumnucleatum, Parvimonas spp. Meta-analysisfecal samples (93)
Gastric cancer Overall diversity of tongue coating microbiota was reduced Tongue coating (94)
Gastric cancer Overall increased microbial diversity in cancer patients Saliva and plaque samples (95)
Gastric cancer 6 bacterial clusters were identified to distinguish cancer patients from controls. (cluster 6 had AUC = 0.76) Tongue coating (96)
Breast cancer Corynebacterium, Staphylococcus, Actinomyces, and Propionibacteriaceae Urine (97)
Breast cancer Fusobacterium, Atopobium, Gluconacetobacter, Hydrogenophaga and Lactobacillus Breast tissue (98)
Breast cancer Coriobacteriaceae Oral rinse (99)