Table 2.
Inflammatory markers cut determination.
| SII cut | Cox HR (95% CI) | p-value | Harrell's C | Somers' D |
|---|---|---|---|---|
| 400 | 2.252 (1.358–3.735) | 0.002 | 0.600 | 0.199 |
| 500 | 2.251 (1.465–3.460) | <0.001 | 0.617 | 0.234 |
| 600 | 2.261 (1.496–3.418) | <0.001 | 0.624 | 0.248 |
| 650 | 2.270 (1.509–3.413) | <0.001 | 0.622 | 0.244 |
| 700 | 2.343 (1.559–3.520) | <0.001 | 0.624 | 0.248 |
| 750 | 2.220 (1.477–3.335) | <0.001 | 0.618 | 0.236 |
| 800 | 2.300 (1.529–3.460) | <0.001 | 0.618 | 0.236 |
| 900 | 2.214 (1.462–3.353) | <0.001 | 0.607 | 0.214 |
| 1,000 | 1.927 (1.249–2.972) | 0.003 | 0.585 | 0.171 |
| NLR cut | Cox HR (95% CI) | p-value | Harrell's C | Somers' D |
| 2.00 | 2.368 (1.452–3.860) | <0.001 | 0.602 | 0.204 |
| 2.35 | 2.335 (1.519–3.489) | <0.001 | 0.621 | 0.241 |
| 2.40 | 2.410 (1.568–3.704) | <0.001 | 0.625 | 0.250 |
| 2.45 | 2.343 (1.530–3.589) | <0.001 | 0.623 | 0.246 |
| 2.50 | 2.363 (1.551–3.600) | <0.001 | 0.626 | 0.252 |
| 2.55 | 2.226 (1.471–3.368) | <0.001 | 0.623 | 0.247 |
| 2.60 | 2.156 (1.430–3.251) | <0.001 | 0.619 | 0.238 |
| 2.70 | 2.190 (1.445–3.293) | <0.001 | 0.620 | 0.240 |
| 2.75 | 2.176 (1.448–3.271) | <0.001 | 0.621 | 0.242 |
| 2.80 | 2.228 (1.483–3.347) | <0.001 | 0.625 | 0.251 |
| 2.85 | 2.206 (1.468–3.316) | <0.001 | 0.618 | 0237 |
| 2.90 | 2.206 (1.468–3.316) | <0.001 | 0.618 | 0.237 |
| 3.50 | 2.075 (1.373–3.137) | <0.001 | 0.606 | 0.211 |
| LMR cut | Cox HR (95% CI) | p-value | Harrell's C | Somers' D |
| 3.0 | 0.663 (0.423–1.037) | 0.072 | 0.550 | 0.100 |
| 3.5 | 0.570 (0.379–0.856) | 0.007 | 0.579 | 0.158 |
| 4.0 | 0.482 (0.321–0.726) | <0.001 | 0.605 | 0.210 |
| 4.3 | 0.454 (0.300–0.689) | <0.001 | 0.613 | 0.226 |
| 4.5 | 0.445 (0.290–0.680) | <0.001 | 0.617 | 0.233 |
| 4.6 | 0.445 (0.290–0.681) | <0.001 | 0.617 | 0.233 |
| 4.7 | 0.422 (0.274–0.650) | <0.001 | 0.622 | 0.244 |
| 4.8 | 0.454 (0.295–0.700) | <0.001 | 0.612 | 0.224 |
| 4.9 | 0.452 (0.292–0.699) | <0.001 | 0.612 | 0.225 |
| 5.0 | 0.482 (0.311–0.749) | 0.001 | 0.603 | 0.206 |
| 5.5 | 0.466 (0.283–0.765) | 0.003 | 0.587 | 0.173 |
NLR, neutrophil-to-lymphocyte ratio; HR, hazard ratio; LMR, lymphocyte-to-monocyte ratio; SII, systemic immune-inflammation index; CI, confidence interval. Bold values represent the optimal cut off point whose C-index is the highest.