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. 2020 Oct 23;10:562253. doi: 10.3389/fonc.2020.562253

FIGURE 6.

FIGURE 6

LINC02381 overexpression effect on the EMT phenotype. (A) RT-qPCR analysis of EMT markers expression in AGS and MKN45 cells transfected with LINC02381 expressing vector, compared with control transfected cells. The expression level of all of EMT markers has been reduced following the LINC02381 overexpression, in both cell lines. Data represent the mean ± SEM from three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001. (B,C) Shows Transwell assay administrated 24 h after LINC02381 or control vector transfection. Bar plot analysis of the migrated cells indicated reduced rate of migration, following the LINC02381 overexpression in both cell lines. Data are shown as mean ± SEM. **P < 0.01. (D,E) In vitro wound healing analysis of AGS cells transfected with LINC02381 expressing or control vectors. Results indicate that LINC02381 overexpression reduces migration capability of the cells.