Table 1.
Definitions of dysplasia.
| Author (Year) | Definition | Reference No. |
|---|---|---|
| Pindborg (1977) | ‘The term used for a lesion in which part of thickness of the epithelium is replaced by cells showing varying degree of atypia’. | 7 |
| Kumar (1992) | ‘It is a disturbance in maturational sequence of stratified squamous epithelium and disturbance in cell kinetics of the proliferative compartment with cytological changes’. | 7 |
| Freedmen & Stanley Kerpel (1995) | ‘Oral epithelial dysplasia is the diagnostic term used to describe the histopathological changes seen in chronic, progressive and premalignant disorders of oral mucosa’. | 8 |
| Jesper Reibel (2003) | ‘Epithelial dysplasia is defined as "histological changes in which the risk for development of a carcinoma is higher than in non-dysplastic epithelium’. | 3 |
| Sharma N et al., (2010) | ‘Dysplasia means abnormal, atypical proliferation encountered principally in the epithelium’. | 7 |
| Pereira JDS et al., (2011) | ‘Oral epithelial dysplasias are potentially malignant disorders characterized by diverse degrees of cellular atypia’. | 9 |
| Goyal P et al., (2012) | ‘Oral epithelial dysplasia is the diagnostic term used to describe the histopathological changes seen in a chronic, progressive and a premalignant disorder of oral mucosa’. | 9 |
| Rastogi V et al., (2013) | ‘Dysplasia refers to a series of subtle in cells signifies that anaplasia will develop soon’. | 6 |
| WHO (2017 ) | ‘Oral epithelial dysplasia as a spectrum of architectural and cytological epithelial changes caused by accumulation of genetic changes, associated with an increased risk of progression to squamous cell carcinoma.’ | 4 |