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. 2020 Oct 23;12:590530. doi: 10.3389/fnagi.2020.590530

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Copyright © 2020 Chen, Chao, Lu, Zhang, Huang, Yang, Qiu, Yang, Zhao, Wang, Li and Tang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The total length of the capillaries in the white matter of the three groups: the 18-month-old control group (18 m control), 28-month-old control group (28 m control), and 28-month-old runner group (28 m runner). (B) The absolute distributions of the total length of the capillaries within the white matter of the three groups. (C) The total surface area of the capillaries in the white matter of the three groups. (D) The absolute distributions of the total surface area of the capillaries within the white matter of the three groups. (E) The total volume of the capillaries in the white matter of the three groups. (F) The absolute distributions of the total volume of the capillaries within the white matter of the three groups. ^∗p < 0.05 when 28 m control is compared to 18 m control. ^∗∗p < 0.01 when 28 m control is compared to 18 m control.^#p < 0.05 when 28 m control is compared to 28 m runner. ^##p < 0.01 when 28 m control is compared to 28 m runner. ^p < 0.05 when 18 m control is compared to 28 m runner.