Figure 2.

Footpad swelling and lesion onset. (A) The footpads of mice were monitored on a daily basis, after challenging with L. major^EGFP. By the end of the 8th week, unlike the other groups, the ILL+CpG group showed no lesion at the injection site. (B) After challenge with L. major^EGFP, footpad swelling was measured using a metric caliper, twice a week. As shown, the PBS group had the earliest lesion onset. (C) In addition, the footpads' diameter of the ILL+CpG group was at the basic level during the 8 weeks follow up. Data are shown as median with range. (n = 4 per group). I.L.L (Iranian Lizard Leishmania), ILL+CpG (Iranian Leishmania Lizard+CpG).