Figure 3.

(A), Frequency of endorsed symptoms at baseline in 61 subjects across high and low blast exposed groups. Tinnitus (ringing in the ear) was the highest reported symptom, endorsed by 29 participants; (B–D), differentially methylated regions and associated genes that track with the reported symptom of tinnitus, headache, sleep difficulties in high relative to low lifetime blast exposed groups, showing gain of methylation in red and loss of methylation in blue, with mean methylation (represented as M-values) across CpG sites (between the high group relative to the low blast exposed group) shown on the y-axis.