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. 2020 Oct 23;11:590365. doi: 10.3389/fgene.2020.590365

Table 4.

Haplotype frequencies of rs17016188 and rs7684892 in PD cases and controls.

rs17016188 rs7684892 Control, n (%) PD, n (%) OR (95% CI) p
Total
T G 479 (47.2) 406 (39.6) 0.731 (0.614–0.872) 4.8 × 10–4*
C G 345 (34.0) 392 (38.2) 1.199 (1.001–1.437) 0.049
T A 190 (18.7) 228 (22.2) 1.239 (0.999–1.538) 0.051
Total 1,014 (100) 1,026 (100) 0.002*
Men
T G 288 (50.2) 194 (36.7) 0.577 (0.453–0.734) 7.14 × 10–6*
C G 186 (32.4) 215 (40.7) 1.433 (1.120–1.833) 0.004*
T A 100 (17.4) 119 (22.5) 1.380 (1.025–1.857) 0.033
Total 574 (100) 528 (100) 4.08 × 10–5*
Women
T G 191 (43.4) 212 (42.6) 0.966 (0.746–1.252) 0.796
C G 159 (36.1) 177 (35.5) 0.974 (0.746–1.273) 0.850
T A 90 (20.5) 109 (21.9) 1.090 (0.796–1.492) 0.592
Total 440 (100) 498 (100) 0.866

CI, confidence interval; OR, odds ratio; PD, Parkinson’s disease.

*

Indicates p < 0.017 after Bonferroni correction.